Tsunade can use her medical ninjutsu to regenerate lost body parts and heal severe injuries. This skill is among the reasons she was chosen as one of the leaders of the Hidden Leaf Village.
She turned to Shizune. "Prepare the antidote. We need something that can counteract this poison without putting him at risk."
Tsunade's actions and her role in the series also reflect the Will of Fire, the foundational philosophy of the Hidden Leaf Village that emphasizes the protection of one's friends and village.