Because Fusion 360 relies heavily on cloud data management, frequent updates, and locally installed background services, creating a truly functional portable version is complex and often violates Autodesk's terms of service.
: While the software isn't portable, your files can be. You can export designs as .f3d or .f3z files to a flash drive to move them between offline-capable workstations. System Requirements for Installation autodesk+fusion+360+portable+install