If the audio loops or cracks, it is a sign your CPU cannot maintain full speed. Enable the "Async Mix" audio setting in the SPU2-X plugin configuration. This separates the audio thread from the video framerate, preventing the sound from slowing down if your FPS dips.
To help you get the best performance out of the game, could you tell me: Are you playing on a ? naruto shippuden ultimate ninja 6 ps2 rom work
Adds characters from later stages of Shippuden and Boruto that were never in the original game, such as Adult Naruto, Sasuke (The Last), and various Otsutsuki members. If the audio loops or cracks, it is
"This is the Pain Arc storyline," Jun noted between rounds If the audio loops or cracks